Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl-

Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl- - Names and Identifiers

Name	1-Phenyl-1,2,3,4-tetrahydro-isoquinoline
Synonyms	Phenyl-tiq 1-Phenyl-1,2,3,4-Tetrahydroiso 1,2,3,4-tetrahydro-1-phenylisoquinoline 1-phenyl-1,2,3,4-tetrahydroisochinoline 1,2,3,4-Tetrahydro-1-phenylisoquinoline 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl- (RS)-1-phenyl-1,2,3,4-tetrahydroisoquinoline 1-Phenyl-2,3,4,9-tetrahydro-1H-carboline-3-carboxylicacid
CAS	22990-19-8
EINECS	248-592-1
InChI	InChI=1/C15H15N/c1-2-7-13(8-3-1)15-14-9-5-4-6-12(14)10-11-16-15/h1-9,15-16H,10-11H2

Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl- - Physico-chemical Properties

Molecular Formula	C15H15N
Molar Mass	209.29
Density	1.065±0.06 g/cm3(Predicted)
Melting Point	98.0 to 102.0 °C
Boling Point	338.4±11.0 °C(Predicted)
Flash Point	166.9°C
Solubility	Chloroform (Slightly), Methanol (Slightly)
Vapor Presure	9.87E-05mmHg at 25°C
Appearance	Solid
Color	Off-White
Maximum wavelength(λmax)	['265nm(EtOH)(lit.)']
pKa	8.91±0.40(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature
Refractive Index	1.589

Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl- - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

Isoquinoline, 1,2,3,4-tetrahydro-1-phenyl- - Introduction

1-Phenyl-1,2,3,4-tetrahydro-isoquinoline, also known as 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline, is an organic compound. The following is a description of its nature, use, formulation and safety information:

Nature:
1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a colorless to light yellow liquid with a special aromatic smell at room temperature. It can be dissolved in some organic solvents, such as alcohol, ether and aromatic hydrocarbon solvents. It has a melting point between -3 ° C and 2 ° C and a boiling point between 160 ° C and 165 ° C.

Use:
1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is often used as an intermediate in the synthesis of other organic compounds in organic synthesis. It can be used to prepare a variety of compounds containing isoquinoline structure, such as drugs, pesticides and dyes.

Method:
The preparation methods of 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline are diverse and can be synthesized through a variety of reaction pathways. One of the common methods is the condensation reaction of an alkyl hydroquinone with an acyloxime under acidic conditions to give 1-Phenyl-1,2,3,4-tetrahydro-isoquinoline.

Safety Information:
1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is relatively safe under normal use and storage conditions. However, as an organic compound, it is a fire hazard and should be kept away from open flames and high temperatures. During operation, direct contact with skin and eyes should be avoided, and appropriate protective equipment should be worn when using. In case of accidental contact, rinse immediately with plenty of water and seek medical treatment. In addition, it should be operated in a well-ventilated area to avoid inhalation of gases or vapors.

Last Update：2024-04-09 20:52:54